2020Journal Article ER2 Auteurs : Ly, Océane; Monchau, Francine; Rémond, Sébastien; Lors, Christine; Jouanneaux, Alain; Debarre, Étienne; Damidot, Denis Optimization of the formulation of an original hydrogel-based bone cement using a mixture design In: Journal of the Mechanical Behavior of Biomedical Materials, vol. 110, pp. 103886, 2020, ISSN: 1751-6161, (ACL). Abstract | Links @article{LY2020103886,
title = {Optimization of the formulation of an original hydrogel-based bone cement using a mixture design},
author = {Océane Ly and Francine Monchau and Sébastien Rémond and Christine Lors and Alain Jouanneaux and Étienne Debarre and Denis Damidot},
url = {https://www.sciencedirect.com/science/article/pii/S1751616120304409},
doi = {https://doi.org/10.1016/j.jmbbm.2020.103886},
issn = {1751-6161},
year = {2020},
date = {2020-01-01},
journal = {Journal of the Mechanical Behavior of Biomedical Materials},
volume = {110},
pages = {103886},
abstract = {Highly swelling polymers, i.e. superabsorbent hydrogels, are hydrophilic, three dimensional networks that can easily absorb a significant amount water, fluid or drug. They are widely used in various applications such as foods, cosmetics, and medical devices. Bone cements are used in orthopaedics as a filling biomaterial or as a grout enhancing the embedding of a prosthesis into bone and fixation is achieved by mechanical interlock with metal or bone surfaces. Recently, hydrophilic bone cements have attracted the attention for bone tissue-engineering applications. Here a bone cement containing an acrylic hydrogel (HEMA) as a liquid phase and a blend of corn starch, cellulose acetate and bioceramic filler as a solid phase is investigated by means of a mixture design which is a special topic within statistical Design of Experiments (DoE). Output variables of interest, complex shear modulus, compressive modulus and swelling rate related to rheological, mechanical and swelling properties respectively, are measured for each cement formulation. Applying the mixture design strategy enables to assess the impact of the three powder components on each variable of interest and to determine the optimal formulation in order to achieve the required properties of this HEMA-based bone cement, especially the rheology adapted to the desired clinical application, but also appropriate mechanical and swelling properties.},
note = {ACL},
keywords = {ER2},
pubstate = {published},
tppubtype = {article}
}
Highly swelling polymers, i.e. superabsorbent hydrogels, are hydrophilic, three dimensional networks that can easily absorb a significant amount water, fluid or drug. They are widely used in various applications such as foods, cosmetics, and medical devices. Bone cements are used in orthopaedics as a filling biomaterial or as a grout enhancing the embedding of a prosthesis into bone and fixation is achieved by mechanical interlock with metal or bone surfaces. Recently, hydrophilic bone cements have attracted the attention for bone tissue-engineering applications. Here a bone cement containing an acrylic hydrogel (HEMA) as a liquid phase and a blend of corn starch, cellulose acetate and bioceramic filler as a solid phase is investigated by means of a mixture design which is a special topic within statistical Design of Experiments (DoE). Output variables of interest, complex shear modulus, compressive modulus and swelling rate related to rheological, mechanical and swelling properties respectively, are measured for each cement formulation. Applying the mixture design strategy enables to assess the impact of the three powder components on each variable of interest and to determine the optimal formulation in order to achieve the required properties of this HEMA-based bone cement, especially the rheology adapted to the desired clinical application, but also appropriate mechanical and swelling properties. |
2012Journal Article ER2 Auteurs : Debarre, Etienne; Hivart, Philippe; Baranski, Didier; Déprez, Pascal Le prototypage rapide, une aide au diagnostic en chirurgie orthopédique et traumatologique. Méthodologie et exemples d’applications cliniques In: Revue de Chirurgie Orthopédique et Traumatologique, vol. 98, no. 5, pp. 519-524, 2012, ISSN: 1877-0517, (ACL). Abstract | Links @article{DEBARRE2012519,
title = {Le prototypage rapide, une aide au diagnostic en chirurgie orthopédique et traumatologique. Méthodologie et exemples d’applications cliniques},
author = {Etienne Debarre and Philippe Hivart and Didier Baranski and Pascal Déprez},
url = {https://www.sciencedirect.com/science/article/pii/S1877051712002420},
doi = {10.1016/j.rcot.2012.06.061},
issn = {1877-0517},
year = {2012},
date = {2012-01-01},
journal = {Revue de Chirurgie Orthopédique et Traumatologique},
volume = {98},
number = {5},
pages = {519-524},
abstract = {Résumé
Complétant l’imagerie médicale, une réplique 3D d’une zone anatomique d’intérêt peut être un avantage non négligeable en chirurgie orthopédique et traumatologique. À la différence du 3D virtuel, elle rend palpable la notion d’échelle et de volume, apparents des détails cachés ou ambigus, ainsi facilitant le diagnostic et la solution chirurgicale. Les données tomodensitométriques du patient, au standard DICOM3, sont exploitées pour une reconstruction 3D numérique suivie d’un prototypage rapide par dépôt de fil fondu d’une réplique en acrylonitrile-butadiène-styrène (ABS) de la zone concernée. Trois applications sont présentées : ostéotomie de cal vicieux épiphysaire, arthroplastie d’épaule et trochléoplastie fémorale. La taille réelle des répliques (réalisées en moins de 30heures) permet une excellente représentation spatiale avec estimation du stock osseux disponible et matérialisation du relief. Le procédé s’avère pertinent (et raisonnable du point de vue économique), même dans les cas courants, dès qu’il est question de géométrie complexe et de représentation objective de l’échelle des volumes.},
note = {ACL},
keywords = {ER2},
pubstate = {published},
tppubtype = {article}
}
Abstract
Complétant l’imagerie médicale, une réplique 3D d’une zone anatomique d’intérêt peut être un avantage non négligeable en chirurgie orthopédique et traumatologique. À la différence du 3D virtuel, elle rend palpable la notion d’échelle et de volume, apparents des détails cachés ou ambigus, ainsi facilitant le diagnostic et la solution chirurgicale. Les données tomodensitométriques du patient, au standard DICOM3, sont exploitées pour une reconstruction 3D numérique suivie d’un prototypage rapide par dépôt de fil fondu d’une réplique en acrylonitrile-butadiène-styrène (ABS) de la zone concernée. Trois applications sont présentées : ostéotomie de cal vicieux épiphysaire, arthroplastie d’épaule et trochléoplastie fémorale. La taille réelle des répliques (réalisées en moins de 30heures) permet une excellente représentation spatiale avec estimation du stock osseux disponible et matérialisation du relief. Le procédé s’avère pertinent (et raisonnable du point de vue économique), même dans les cas courants, dès qu’il est question de géométrie complexe et de représentation objective de l’échelle des volumes. |
2012Journal Article ER2 Auteurs : Debarre, Etienne; Hivart, Philippe; Baranski, D; Déprez, Pascal Speedy skeletal prototype production to help diagnosis in orthopaedic and trauma surgery. Methodology and examples of clinical applications In: Orthopaedics & Traumatology: Surgery & Research, vol. 98, no. 5, pp. 597–602, 2012. Links @article{Debarre_2012,
title = {Speedy skeletal prototype production to help diagnosis in orthopaedic and trauma surgery. Methodology and examples of clinical applications},
author = {Etienne Debarre and Philippe Hivart and D Baranski and Pascal Déprez},
doi = {10.1016/j.otsr.2012.03.016},
year = {2012},
date = {2012-09-01},
journal = {Orthopaedics & Traumatology: Surgery & Research},
volume = {98},
number = {5},
pages = {597--602},
publisher = {Elsevier BV},
keywords = {ER2},
pubstate = {published},
tppubtype = {article}
}
|
2009Journal Article ER2 Auteurs : Deprez, Pascal; Hivart, Philippe; Coutouly, J F; Debarre, Etienne Friction and wear studies using Ŧaguchi method: application to thecharacterization of carbon-silicon carbide tribological couples ofautomotive water pump seals. In: Advances in Materials Science and Engineering, vol. vol. 2009,, no. article ID830476,, 2009, (ACL). @article{DEPR2009Ab,
title = {Friction and wear studies using Ŧaguchi method: application to thecharacterization of carbon-silicon carbide tribological couples ofautomotive water pump seals.},
author = {Pascal Deprez and Philippe Hivart and J F Coutouly and Etienne Debarre},
year = {2009},
date = {2009-01-01},
journal = {Advances in Materials Science and Engineering},
volume = {vol. 2009,},
number = {article ID830476,},
note = {ACL},
keywords = {ER2},
pubstate = {published},
tppubtype = {article}
}
|
